It is estimated that bone marrow transplant treatment has been rendered to the critical patients suffering from deadly afflictions like life-threatening blood disorders, debilitated internal immunity or metabolic abnormalities in the body for more than fifty years. This journey of medical science has been a continuous process of evolution and improvement focusing on systematically eliminating the disadvantages and hazards and slowly converting it in to a successful mechanism of dealing with menacing diseases to which doctors and patients surrendered helplessly at one point of time. Today, therefore the ambit of this treatment has grown manifold wherein the healthcare professionals are considering many more variables in order to gauge the degree of risk that the patient has to undertake. This holistic medical perspective is helping the bone marrow transplant survival rate to a great extent for provisioning a result oriented treatment process.
Administrating the entire treatment procedure is an exceedingly challenging process and entails a comprehensive profiling of the patients and comparing different treatment methods which will be compatible with the patient’s health condition so as to increase bone marrow transplant survival rate by decreasing the intensity of complications which the patients have to withstand after the treatment. The quotients which may impact the fate of the transplantation are the type of cancer, the stage of cancer, assessment of the underlying health disorders existing in the patient and last but not the least his age play pivotal role in the transplantation. Moreover, the oncologists prefer to compare and match these parameters in order to determine the type of transplant and the source of the hematopoietic cells which are equally relevant for the course of the treatment. Bone marrow transplant is one of the earliest discovered transplant procedures which was primarily used for treating blood related malignancies like leukemia and lymphoma among others. The treatment entails destruction of the diseased stem cells which proliferate at an alarming rate thereby affecting the equilibrium of the entire body and eventually affecting the healthy functioning of the body.
Once the body is successfully rid of the malignant cells after the application of chemotherapy or radiation the patient is then prepared for the transfusion of the fresh stem cell transplantation. This preparation phase which is also known as conditioning regimen in medical parlance. This prescription by the doctors essentially involves intake of very strong medication which is instrumental for getting rid of the residual diseased stem cells from the system so that when the transplanted is effected in allogeneic mode it does not give rise to serious complications. It has been observed that when the healthy cells infused in the patient’s body starts attacking the remaining malignant cells creating graft-versus-host syndrome which may cause relapse and call for an immediate second phase of transplantation to stabilize the situation. This preparedness of medical science to combat the clinical odds has further improved bone marrow transplant survival rate.